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The main component of the nutritional supplement against oncological diseases is the natural substance sulforaphane. It is scientifically proven that by taking it regularly you will build up protection against degenerative diseases, oxidative stress or chronic inflammation.
Slovak scientist Prof. RNDr. Katarína Horáková, DrSc., was a member of the scientific research team of isothiocyanate experts at the current Faculty of Chemical and Food Technology of the Slovak Technical University in Bratislava. She was the first in the world in the late 1950s to investigate and discover the anticancer effect of the natural isothiocyanate sulforaphane on human cancer cells in vitro. The result of her research work is Sulforaphane EXTRA, an exceptional nutraceutical, which is produced on the basis of her formula.
The development of this exceptional nutraceutical has not been easy and the road has been a winding one. It can be said that Prof. Katarína Horáková has devoted most of her life to the research of isothiocyanates (ITKs), which include sulforaphane. She became aware of the existence of isothiocyanates as such in 1956 when she was still a student at the Faculty of Science of the Charles University, where she studied biology. She first came into direct contact with ITK in the laboratory of Prof. Ing. Ľudovít Drobnic, DrSc. She became a member of the ITK research team, which began to research the effects of ITK not only on microorganisms, but also on cancer cells. The results of her experiments were published by Prof. Horáková in 1958 in the Slovak oncological journal Neoplasma.This publication caused a huge stir among oncologists because it proved that ITK could have not only an antimicrobial but also an anti-tumour effect in an unprecedented way.
After defending her thesis in 1958, she was given the task of setting up a tissue culture laboratory. It was the first cell culture laboratory in Czechoslovakia where she began to systematically study the cytotoxic effect of new biologically activewith the intention of discovering substances with anticancer and antioxidant properties. She and her colleagues published the results of these studies in the Slovak Academy of Sciences oncology journal Neoplasma after they were rejected for publication in the American scientific journal Cancer Research. The American authors initially ignored their research team’s publications. It was only many years later that she was contacted by American scientists also researching the effects of ITK on tumour cells, who had sought her research with sulforaphane, and offered to collaborate with her.Together with her research team, Prof. Katarína Horáková gave her American colleagues an incentive, on the basis of which they developed a unique product. They succeeded in placing a broccoli extract containing glucoraphanin and the enzyme myrosinase, which is essential for the release of sulforaphane, into a single capsule. All that was left was to devise a way to block the activity of the myrosinase enzyme for the necessary time before the capsule reached its destination in our bodies, the small intestine. The result is sulforaphane, a unique molecule provided to mankind by nature.
“I have worked in laboratories for many years, and much of that time has been devoted to isothiocyanate research. My goal was to discover the fantastic potential that some of them held and to use them to prevent human health problems. I played my part in the creation of the cutting-edge nutritional supplement Sulforaphane Extra.I believe and am convinced that with its healing properties it will bring back health to all who take it.“
Sulforaphane is a natural substance that is rich in sulfur. In its inactive form, it is found as glucoraphanin in brassica vegetables (e.g. broccoli, cabbage, cauliflower, kale, kohlrabi, brussels sprouts). Glucoraphanin requires the plant enzyme myrosinase for its conversion to sulforaphane, which is released during the chewing of raw vegetables. It is myrosinase that converts glucoraphanin in the body into sulforaphane and also amplifies its effects.
The advantage of sulforaphane is its high bioavailability. Thanks to its ability to merge with fats, it reaches all the cells of our body. Based on pharmacodynamic studies, sulforaphane has been shown to have an absolute bioavailability of up to around 80%. It peaks in the bloodstream approximately 1 hour after ingestion and remains active for up to 20 hours.
Sulforaphane is said by scientists to hold truly incredible therapeutic potential. How can sulforaphane positively affect such a wide range of health problems?Scientists have searched for the answer to this question in hundreds of clinical studies and have concluded that chronic inflammation and oxidative stress are the two common primary causes of common chronic degenerative human diseases. The results of over 3,000 studies have shown that sulforaphane acts as a health insurance policy for our cells by supporting protective and detoxifying mechanisms. “This allows environmental toxins and air pollutants to be removed from the human bodyand to repair damage caused by oxidative stress and inflammation,” says Professor Horáková.
“Another therapeutic potential of sulforaphane is based on its ability to activate the Nrf2 super regulatory gene, which is found in every cell of our body. When sulforaphane is taken regularly, 500 disease-causing genes are switched off and more than 200 longevity genes are switched on. These genes control the mechanisms cells use to protect themselves from oxidative stress, inflammation, DNA-damaging electrophiles and radiation. Under normal conditions, these protective systems in our cells do not use their maximum capacity. Increasing the level of activity of these systems can be achieved by sulforaphane and thus reducingreduce the risk of cancer and other degenerative chronic diseases,” says Professor Horáková.
Sulforaphane also creates a broad protective shield against cardiovascular disease.”Unlike drugs that specifically act either to lower cholesterol, anti-clotting or help prevent blood vessels from narrowing, thus reducing blood pressure, the dietary chemoprotective agent sulforaphane blocks several steps that together are involved in the pathophysiology of heart and blood vessel disorders. At the same time, it protects against atherosclerosis, high blood pressure, prevents platelet clumping and thrombus formation.”
Sulforaphane blocks several steps involved together in the formation of cancer. This chemoprotective substance attacks from several sides at once: it prevents the growth of human cancer cells, it prevents the action of cancer-promoting substances by “switching on genes that prevent the formation of newm cancer cells, and “switches off” genes that help its formation and spread, in addition to killing cancer stem cells.
Not only does our genetic predisposition play a role in the development of cancer, but many other factors play a role as well. Some of these we cannot control, but there are others that we can. We can focus on cancer prevention by following the principles of healthylifestyle along with the right combination of natural nutritional supplements or nutraceuticals.
https://www.carnomed.sk/produkty/sulforafan-extra.htm
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